The state of the cytokine system in women of different ages
- Authors: Chepurnova N.S.1, Birko O.N.1,2, Yutskovskaya Y.A.2, Gerasimenko L.V.1, Rusanova D.E.1, Petukhova A.G.1, Markelova E.V.1
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Affiliations:
- Federal State Budgetary Educational Institution of Higher Education «Pacific State Medical University» of the Ministry of Health of the Russian Federation
- LLC «Professor’s Clinic of the Yutskovskihs»
- Issue: Vol 19, No 1-4 (2022)
- Pages: 80-83
- Section: Articles
- URL: https://cijournal.ru/1684-7849/article/view/623117
- DOI: https://doi.org/10.17816/CI2022221-4-13
- ID: 623117
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Abstract
The article presents the results of a study of the cytokine profile of venous blood serum of 100 practically healthy women of different age groups (IL-1β, TNF-α, IFN-γ, IL-4 and IL-10), conducted by the sandwich variant of solid-phase enzyme immunoassay. The relative prevalence of Th 1 type of response in practically healthy women in old age is shown, which reflects the intensity of immune reactions against intracellular pathogens and indicates an increase in delayed hypersensitivity processes. The identified features require further study, including taking into account hormonal regulation.
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About the authors
Natalia S. Chepurnova
Federal State Budgetary Educational Institution of Higher Education «Pacific State Medical University» of the Ministry of Health of the Russian Federation
Email: dr.cns@yandex.ru
candidate of medical sciences, associate professor of the department of normal and pathological physiology
Russian Federation, 690950, Vladivostok, Ostryakova Ave., 2Oksana N. Birko
Federal State Budgetary Educational Institution of Higher Education «Pacific State Medical University» of the Ministry of Health of the Russian Federation; LLC «Professor’s Clinic of the Yutskovskihs»
Email: cytokines@yandex.ru
laboratory assistant, dermatologist, cosmetologist
Russian Federation, 690950, Vladivostok, Ostryakova Ave., 2; 690001, Vladivostok, Metallistov str., 3Yana A. Yutskovskaya
LLC «Professor’s Clinic of the Yutskovskihs»
Email: cytokines@yandex.ru
md, professor, dermatologist, cosmetologist
Russian Federation, 690001, Vladivostok, Metallistov str., 3Llilia V. Gerasimenko
Federal State Budgetary Educational Institution of Higher Education «Pacific State Medical University» of the Ministry of Health of the Russian Federation
Email: cytokines@yandex.ru
student of the faculty of medicine
Russian Federation, 690950, Vladivostok, Ostryakova Ave., 2Diana E. Rusanova
Federal State Budgetary Educational Institution of Higher Education «Pacific State Medical University» of the Ministry of Health of the Russian Federation
Email: cytokines@yandex.ru
student of the faculty of medicine
Russian Federation, 690950, Vladivostok, Ostryakova Ave., 2Antonina G. Petukhova
Federal State Budgetary Educational Institution of Higher Education «Pacific State Medical University» of the Ministry of Health of the Russian Federation
Email: cytokines@yandex.ru
student of the faculty of medicine
Russian Federation, 690950, Vladivostok, Ostryakova Ave., 2Elena V. Markelova
Federal State Budgetary Educational Institution of Higher Education «Pacific State Medical University» of the Ministry of Health of the Russian Federation
Author for correspondence.
Email: markev2010@mail.ru
md, professor, head of the department of normal and pathological physiology
Russian Federation, 690950, Vladivostok, Ostryakova Ave., 2References
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