The state of the cytokine system in women of different ages

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The article presents the results of a study of the cytokine profile of venous blood serum of 100 practically healthy women of different age groups (IL-1β, TNF-α, IFN-γ, IL-4 and IL-10), conducted by the sandwich variant of solid-phase enzyme immunoassay. The relative prevalence of Th 1 type of response in practically healthy women in old age is shown, which reflects the intensity of immune reactions against intracellular pathogens and indicates an increase in delayed hypersensitivity processes. The identified features require further study, including taking into account hormonal regulation.

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Sobre autores

Natalia Chepurnova

Federal State Budgetary Educational Institution of Higher Education «Pacific State Medical University» of the Ministry of Health of the Russian Federation

Email: dr.cns@yandex.ru

candidate of medical sciences, associate professor of the department of normal and pathological physiology

Rússia, 690950, Vladivostok, Ostryakova Ave., 2

Oksana Birko

Federal State Budgetary Educational Institution of Higher Education «Pacific State Medical University» of the Ministry of Health of the Russian Federation; LLC «Professor’s Clinic of the Yutskovskihs»

Email: cytokines@yandex.ru

laboratory assistant, dermatologist, cosmetologist

Rússia, 690950, Vladivostok, Ostryakova Ave., 2; 690001, Vladivostok, Metallistov str., 3

Yana Yutskovskaya

LLC «Professor’s Clinic of the Yutskovskihs»

Email: cytokines@yandex.ru

md, professor, dermatologist, cosmetologist

Rússia, 690001, Vladivostok, Metallistov str., 3

Llilia Gerasimenko

Federal State Budgetary Educational Institution of Higher Education «Pacific State Medical University» of the Ministry of Health of the Russian Federation

Email: cytokines@yandex.ru

student of the faculty of medicine

Rússia, 690950, Vladivostok, Ostryakova Ave., 2

Diana Rusanova

Federal State Budgetary Educational Institution of Higher Education «Pacific State Medical University» of the Ministry of Health of the Russian Federation

Email: cytokines@yandex.ru

student of the faculty of medicine

Rússia, 690950, Vladivostok, Ostryakova Ave., 2

Antonina Petukhova

Federal State Budgetary Educational Institution of Higher Education «Pacific State Medical University» of the Ministry of Health of the Russian Federation

Email: cytokines@yandex.ru

student of the faculty of medicine

Rússia, 690950, Vladivostok, Ostryakova Ave., 2

Elena Markelova

Federal State Budgetary Educational Institution of Higher Education «Pacific State Medical University» of the Ministry of Health of the Russian Federation

Autor responsável pela correspondência
Email: markev2010@mail.ru

md, professor, head of the department of normal and pathological physiology

Rússia, 690950, Vladivostok, Ostryakova Ave., 2

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Declaração de direitos autorais © Chepurnova N.S., Birko O.N., Yutskovskaya Y.A., Gerasimenko L.V., Rusanova D.E., Petukhova A.G., Markelova E.V., 2023