Мақаланы E-mail арқылы жіберу INFLUENCE OF POTASSIUM BICHROMATE ON MORPHOLOGICAL AND IMMUNOLOGICAL CHARACTERISTICS OF WISTAR RATS
- Авторлар: Smolyagin A.I.1, Mikhaylova I.V.1, Ermolina E.V.1, Stadnikov A.A.1, Boev V.M.1
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Мекемелер:
- State Budgetary Educational Institution «Orenburg State Medical Academy», Ministry of Health of Russia
- Шығарылым: № 2 (2015)
- Беттер: 40-44
- Бөлім: Articles
- ##submission.datePublished##: 06.04.2015
- URL: https://cijournal.ru/0869-7922/article/view/641321
- DOI: https://doi.org/10.15690/vramn448
- ID: 641321
Дәйексөз келтіру
Толық мәтін
Аннотация
The impact of Potassium Bichromate ( at 1 MAC dose) on morphological and immunological parameters of Wistar rats lymphoid organs was investigated in a chronic experiment (135 days). A lasting uptake of chromium by the Wistar rat organism induces a decrease of thymus mass and thymocytes number, causes a complex of structural and functional alterations evidencing about the status of accidental involution, lymphoreticular hyperplasia and plasmocytic and macrophage transformation of lymphoid nodes and spleen, induces a programmed death of thymocytes and lymphocytes in splenic T-zones and lymphoid nodes. Chromium induces morpho-functional changes in spleen shown by decrease in its weight and number of spelnocytes, lymphoid series cells and on the contrary by increase of erythroid series cells. The impact of chromium on the bone marrow was evident in a decreased level of myeloid series, neutrophils and on the contrary in increased amount of lymphoid cells and the content of erythroid cells as well.
Негізгі сөздер
Авторлар туралы
Aleksandr Smolyagin
State Budgetary Educational Institution «Orenburg State Medical Academy», Ministry of Health of Russia
Хат алмасуға жауапты Автор.
Email: noemail@neicon.ru
Доктор медицинских наук, профессор, заведующий проблемной лабораторией по изучению механизмов естественного иммунитета Оренбургской государственной медицинской академии Минздрава РФ, 460000, г. Оренбург
e-mail: probllab.orenburg@mail.ru
РесейIrina Mikhaylova
State Budgetary Educational Institution «Orenburg State Medical Academy», Ministry of Health of Russia
Email: noemail@neicon.ru
Доктор биологических наук, доцент кафедры химии и фармацевтической химии Оренбургской государственной медицинской академии Минздрава РФ, 460000, г. Оренбург
e-mail: michaylova74@yandex.ru
РесейEvgenija Ermolina
State Budgetary Educational Institution «Orenburg State Medical Academy», Ministry of Health of Russia
Email: noemail@neicon.ru
Кандидат биологических наук, старший научный сотрудник проблемной лаборатории по изучению механизмов естественного иммунитета Оренбургской государственной медицинской академии Минздрава РФ, 460000, г. Оренбург
e-mail: probllab.orenburg@mail.ru
РесейAleksandr Stadnikov
State Budgetary Educational Institution «Orenburg State Medical Academy», Ministry of Health of Russia
Email: noemail@neicon.ru
Доктор биологических наук, профессор, заведующий кафедрой гистологии, цитологии эмбриологии, 460000, г. Оренбург
e-mail: k_histology@orgma.ru
РесейViktor Boev
State Budgetary Educational Institution «Orenburg State Medical Academy», Ministry of Health of Russia
Email: noemail@neicon.ru
Доктор медицинских наук, профессор, ректор Оренбургской государственной медицинской академии Минздрава РФ, 460000, г. Оренбург
e-mail: probllab.orenburg@mail.ru
РесейӘдебиет тізімі
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