Fe(III), Co(III), and Cu(II) Complexes with Acylhydrazones Containing a Triphenylphosphonium Moiety: Synthesis, Crystal Structure, and Antibacterial Activity

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New acylhydrazones based on para- and meta-nitrobenzhydrazides and substituted salicylic aldehyde containing a triphenylphosphonium fragment were synthesized and spectrally characterized. With these acylhydrazones, a series of new mononuclear coordination compounds of Fe(III), Co(III), and Cu(II) were obtained, the molecular structure of which was determined by single-crystal X-ray diffraction. The antibacterial activity of the isolated acylhydrazones and copper(II) complexes against Staphylococcus aureus and Escherichia coli was studied. It was shown that the transition from an organic compound to a complex one contributes to a significant increase in activity against E. coli.

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作者简介

A. Matiukhina

Kurnakov Institute of General and Inorganic Chemistry of the Russian Academy of Sciences

Email: ezorinatikhonova@igic.ras.ru
俄罗斯联邦, Moscow

E. Zorina-Tikhonova

Kurnakov Institute of General and Inorganic Chemistry of the Russian Academy of Sciences

编辑信件的主要联系方式.
Email: ezorinatikhonova@igic.ras.ru
俄罗斯联邦, Moscow

N. Gogoleva

Kurnakov Institute of General and Inorganic Chemistry of the Russian Academy of Sciences

Email: ezorinatikhonova@igic.ras.ru
俄罗斯联邦, Moscow

L. Popov

Southern Federal University

Email: ezorinatikhonova@igic.ras.ru
俄罗斯联邦, Rostov-on-Don

P. Morozov

Southern Federal University

Email: ezorinatikhonova@igic.ras.ru
俄罗斯联邦, Rostov-on-Don

V. Lazarenko

National Research Center “Kurchatov Institute”

Email: ezorinatikhonova@igic.ras.ru
俄罗斯联邦, Moscow

A. Zubenko

North Caucasus Zonal Research Veterinary Institute, Branch, Federal Rostov Agrarian Research Center

Email: ezorinatikhonova@igic.ras.ru
俄罗斯联邦, Novocherkassk

L. Fetisov

North Caucasus Zonal Research Veterinary Institute, Branch, Federal Rostov Agrarian Research Center

Email: ezorinatikhonova@igic.ras.ru
俄罗斯联邦, Novocherkassk

A. Svyatogorova

North Caucasus Zonal Research Veterinary Institute, Branch, Federal Rostov Agrarian Research Center

Email: ezorinatikhonova@igic.ras.ru
俄罗斯联邦, Novocherkassk

M. Kiskin

Kurnakov Institute of General and Inorganic Chemistry of the Russian Academy of Sciences

Email: ezorinatikhonova@igic.ras.ru
俄罗斯联邦, Moscow

I. Eremenko

Kurnakov Institute of General and Inorganic Chemistry of the Russian Academy of Sciences

Email: ezorinatikhonova@igic.ras.ru
俄罗斯联邦, Moscow

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1. JATS XML
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2. Scheme 1. General scheme for the synthesis of acylhydrazones (H₂L¹)Cl, (H₂L²)Cl and complexes I–VI.

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3. Fig. 1. Structure of complexes II (a) and III (b) (hydrogen atoms are not shown).

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4. Fig. 2. Structure of complexes V (a) and VI (b) (nitrate anions, hydrogen atoms and solvate molecules are not shown).

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5. Additional materials
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