Peptide Amphiphiles for Pharmaceutical Applications


Дәйексөз келтіру

Толық мәтін

Аннотация

During the last few decades, several efforts have been made towards developing biocompatible materials. Among them, peptide amphiphiles (PAs) constitute a novel nanotechnological strategy used in the field of biomedicine since they can provide tissue- specific binding and localization. PAs possess several regions combining hydrophobic and hydrophilic areas that are able to self-assemble in aqueous media, forming different tertiary nanostructures able to interact with cellular membranes. Moreover, these molecules can be tuned by incorporating collagen, lipids, or fluorescent markers. In addition, they can also be used as carriers in order to encapsulate active compounds for drug delivery showing promising features in this area. In this review, the self-assembled structures of PAs as well as their pharmacological applications have been summarized. Furthermore, their use as drug delivery systems has been highlighted and the latest advances in this field have been reviewed.

Авторлар туралы

Mayra Fuertes-Llanos

Department of Pharmacy, Pharmaceutical Technology and Physical Chemistry, Faculty of Pharmacy and Food Sciences,, University of Barcelona

Email: info@benthamscience.net

Maria Gómara

Unit of Synthesis and Biomedical Applications of Peptides, IQAC-CSIC,

Email: info@benthamscience.net

Isabel Haro

Unit of Synthesis and Biomedical Applications of Peptides, IQAC-CSIC

Email: info@benthamscience.net

Elena Sánchez-López

Department of Pharmacy, Pharmaceutical Technology and Physical Chemistry, Faculty of Pharmacy and Food Sciences, University of Barcelona,

Хат алмасуға жауапты Автор.
Email: info@benthamscience.net

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