JUSTIFICATION OF MAXIMUM SINGEL ALLOWABLE CONCENTRATIONS OF 1-METHYL-4-ISOPROPENYLCYCLOHEX-1-ENE (LIMONENE), 3,7,7-TRIMETHYLBICYCLO[4.1.0]HEPT-2-ENE (3-CARENE) AND 2,2-DIMETHYL-3-METHYLENEBICYCLO[2.2.1]HEPTANE (CAMPHENE) IN AMBIENT AIR

Capa

Citar

Texto integral

Resumo

This paper presents the results of the experimental studies on justification of the maximum single allowable concentrations (MAC) of 1-methyl-4-isopropenylcyclohex-1-ene (limonene), 3,7,7-trimethylbicyclo[4.1.0]hept-2-ene (3-carene), and 2,2-dimethyl-3-methylenebicyclo[2.2.1]heptane (camphene) in the air of urban and rural settlements. The research has been carried out in accordance with the current methodology for determining the odor thresholds of substances using modern olfactometric equipment (dynamic olfactometer) and highly sensitive methods for identifying chemical components (chromatography-mass spectrometry). According to the results obtained, the recommended maximum single allowable concentrations in the atmospheric air of urban and rural settlements are 0,08 mg/m3 (hazard class 4) for limonene; 0,2 mg/m3 (hazard class 4) for 3-carene; 0,3 mg/m3 (hazard class 3) for camphene; the limiting indicator of harmfulness for all substances is reflex. An analytical methodic based on chromatography-mass spectrometry and certified in accordance with GOST R 8.563-2009 and GOST R ISO 5725-2002 has been developed to control the concentrations of α-pinene, β-pinene, camphene, 3-carene, and limonene in the atmospheric air of urban and rural settlements.

Sobre autores

O. Budarina

Centre for Strategic Planning and Management of Medical and Biological Health Risks, Ministry of Health of the Russian Federation

Autor responsável pela correspondência
Email: vozduch2002@mail.ru
119121, Moscow Rússia

L. Fedotova

Centre for Strategic Planning and Management of Medical and Biological Health Risks, Ministry of Health of the Russian Federation

Email: fedotov2003@mail.ru
119121, Moscow Rússia

Z. Shipulina

Centre for Strategic Planning and Management of Medical and Biological Health Risks, Ministry of Health of the Russian Federation

Email: vozduch2002@mail.ru
119121, Moscow Rússia

Т. Potapchenko

Centre for Strategic Planning and Management of Medical and Biological Health Risks, Ministry of Health of the Russian Federation

Email: timurpotapchenko@mail.ru
119121, Moscow Rússia

Bibliografia

  1. Hygiene norms GN 2.1.6.2309-07 Atmospheric air and air of the closed rooms, sanitary protection of air. Tentative Safe Exposure Levels (TSEL) of pollutants in the atmospheric air of populated areas. Hygienic standards (Resolution of the Chief state sanitary doctor of the Russian Federation of 19.12.2007 No. 92) (ed. of 21.10.2016) (in Russian).
  2. Materials on justification of TSEL of priority volatile components of tobacco production dust (alpha-pinene; 3-karene; solanone; oxoisopforone; salicylaldehyde). NIIEChiGOS im.A.N.Sysina RAMN – Archive of the Section «Air hygiene». – Manuscript. M.; 2006 (in Russian).
  3. Materials on justification of MPC of turpentine in atmospheric air. NIIOiKG im.A.N.Sysina AMN SSSR – Archive of the Section «Air hygiene». – Manuscript. M.; 1978 (in Russian).
  4. Materials on justification of tentative safe exposure levels of camphene exposure in atmospheric air. NIIOiKG im.A.N.Sysina AMN SSSR – Archive of the Section «Air hygiene». – Manuscript. M.; 1988 (in Russian).
  5. Budarina O.V., Pinigin M.A., Fedotova L.A., Sabirova Z.F., Shipulina Z.V. Substantiation of the maximum one-time permissible concentration of volatile organic compounds formed during high-temperature processing of wood production in the atmospheric air of settlements. Toxicological Review. 2017; 6: 42-7 (in Russian).
  6. Harmful organic substances. Natural organic compounds: publication of reference and encyclopedic type. T.7 / red. V.A. Filov, Yu.I. Musijchuk, V.A. Ivin. – SPb.: Izd-vo SPHFA: NPO Mir i Sem’ya-95, 1998 (in Russian).
  7. Tepikina L.A. On the method of probabilistic estimation of olfactory sensation threshold. Hygienic aspects of environmental protection. M., IOKG im. A.N.Sysina; 1974; 2: 45-7 (in Russian).
  8. Andreeshcheva N.G., Pinigin M.A. Justification of the maximum single MPC of atmospheric pollutants by their probabilistic thresholds of smell, hazard classes and safety factors. Hygienic aspects of environmental protection. M., IOKG im.A.N.Sysina, 1978; 6: 75-6 (in Russian).
  9. Budarina O.V., Pinigin M.A., Fedotova L.A., Sabirova Z.F., Potapchenko T.D. Modern methodological approaches to the experimental justification of the permissible content of substances with odor in the atmospheric air. Toxicological Review. 2017; 4: 34-9 (in Russian).
  10. Temporary guidelines for justification of maximum permissible concentrations (MPC) of pollutants in the air of populated areas. №4681-88, MZ USSR, M., 1989 (in Russian).
  11. European standard «CEN (2003). Air quality – Determination of odour concentration by dinamic olfactometry. EN 13725:2003», European committee for standardisation.
  12. Mannebek D. Determination of the level of smell. Olfactometric equipment. Collection of reports of the international conference “Current issues of smell assessment and regulation”. M.: Liggett-Ducat, 2006, Pp. 124-145 (in Russian).
  13. Budarina O.V., Fedotova L.A., Shipulina Z.V., Potapchenko T.D. Toxicity of 4,6,6-trimethylbicyclo[3.1.1]hept-3-ene (α-pinene) and 6,6-dimethyl-2-methylbicyclo[3.1.1]heptane (β-pinene). Toxicological Review. 2018; 5(152): 49-52 (in Russian).
  14. Resolution of the Chief state sanitary doctor of the Russian Federation of 31.05.2018 No. 37 “Changes in hygienic standards GN 2.1.6.3492-17 “Maximum permissible concentrations (MPC) of pollutants in the atmospheric air of urban and rural settlements”. Available at: https://www.law.ru/npd/doc/docid/550415449/modid/99.

Arquivos suplementares

Arquivos suplementares
Ação
1. JATS XML
Baixar

Declaração de direitos autorais © Budarina O.V., Fedotova L.A., Shipulina Z.V., Potapchenko Т.D., 2020


СМИ зарегистрировано Федеральной службой по надзору в сфере связи, информационных технологий и массовых коммуникаций (Роскомнадзор).
Регистрационный номер и дата принятия решения о регистрации СМИ: серия ПИ № ФС 77 - 81728 от 11 декабря 2013.