Furanocoumarins: History of Research, Diversity, Synthesis, Physiological Role in the Plant, and Medical Application

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Abstract

The review is devoted to furanocoumarins, a class of substances that are a combination of pyrone,
benzene, and furan rings, possessing a system of conjugated double bonds (which in some cases can be disrupted). This group of compounds is currently being widely studied due to its phototoxic and medicinal properties. The work examines furanocoumarins of natural origin, identified in the family Umbelliferae, or Apiaceae, their diversity is structured; the history of their study, the currently known stages of their biosynthesis,
and examples of their biological activity in plants, cell culture and for medical use are described.

About the authors

V. Yu. Shtratnikova

Belozersky Research Institute of Physical and Chemical Biology; Moscow State University

Author for correspondence.
Email: vtosha@yandex.ru
Moscow, Russia

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